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Methyl 2-O,3-O,4-o-Tris(Trimethylsilyl)-6-Deoxy-α-L-Galactopyranoside CAS NO 56271-58-0


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CAS No.:56271-58-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-O,3-O,4-o-Tris(trimethylsilyl)-6-deoxy-α-L-galactopyranoside is a specialized, high-purity silylated carbohydrate derivative, primarily utilized as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. Its value lies in enabling complex, multi-step reactions with high selectivity and yield, which is critical for research and development in demanding fields. This compound is essential for pharmaceutical chemists, process development scientists, and researchers working on nucleoside analogs, complex glycoconjugates, and other fine chemicals where precise stereochemistry and functional group manipulation are paramount.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs, antiviral agents, and other complex active pharmaceutical ingredients (APIs).
  • Glycochemistry Research: Used in the study and synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics due to its protected galactose scaffold.
  • Protecting Group Strategy: The trimethylsilyl (TMS) groups serve as temporary protecting agents for hydroxyl functions, allowing for selective reactions at other sites on the molecule.
  • Process Chemistry: Employed in route scouting and scale-up for the production of high-value fine chemicals and specialty materials.
  • Bioconjugation & Probe Development: Acts as a precursor for labeled sugars used in biochemical assays, imaging probes, and diagnostic tools.
  • Academic & Industrial R&D: A valuable reagent for methodology development in synthetic organic chemistry, particularly in carbohydrate and medicinal chemistry.

Basic Information

Item Details
Product Name Methyl 2-O,3-O,4-o-Tris(trimethylsilyl)-6-deoxy-α-L-galactopyranoside
CAS No. 56271-58-0
Molecular Formula C16H38O5Si3
Molecular Weight 394.73 g/mol
Synonyms Methyl 2,3,4-Tri-O-(trimethylsilyl)-6-deoxy-α-L-galactopyranoside; 6-Deoxy-α-L-galactopyranoside, methyl 2,3,4-tris-O-(trimethylsilyl)-; Methyl 6-deoxy-2,3,4-tri-O-trimethylsilyl-α-L-galactopyranoside; α-L-Galactopyranoside, methyl 6-deoxy-2,3,4-tris-O-(trimethylsilyl)-; TMS-protected methyl α-L-fucopyranoside derivative; Silylated methyl 6-deoxy-α-L-galactoside
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Quality Control

Every batch of Methyl 2-O,3-O,4-o-Tris(trimethylsilyl)-6-deoxy-α-L-galactopyranoside is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry and research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid or low-melting solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0% (Area %)
Assay (GC or HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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