Description

1-O,3-O,4-o-Tris(Trimethylsilyl)-2-Deoxy-D-Erythro-Pentopyranose is a key protected carbohydrate intermediate, specifically a fully silylated 2-deoxypentose derivative. This compound is essential for synthetic chemists as it provides a versatile, reactive scaffold for the controlled construction of complex nucleoside analogs and other bioactive molecules. It is primarily utilized in pharmaceutical research and development for the synthesis of antiviral and anticancer agents, as well as in advanced organic synthesis for creating chiral building blocks.

Application

• Nucleoside & Nucleotide Synthesis: A crucial protected intermediate for the preparation of modified nucleosides used in antiviral and anticancer drug discovery.
• Pharmaceutical Intermediates: Serves as a key chiral building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Used in the study and synthesis of deoxy sugars and their conjugates for biochemical research.
• Oligonucleotide Synthesis: Acts as a monomer precursor for the development of modified oligonucleotides with therapeutic potential.
• Glycoconjugate Research: Employed in the preparation of glycoconjugates for probing biological recognition processes.
• Process Chemistry & Scale-up: Suitable for use in process development and pilot-scale manufacturing of specialty fine chemicals.

Basic Information

Product Name	1-O,3-O,4-o-Tris(Trimethylsilyl)-2-Deoxy-D-Erythro-Pentopyranose
CAS No.	56227-34-0
Molecular Formula	C14H34O4Si3
Molecular Weight	350.67 g/mol
Synonyms	2-Deoxy-D-erythro-pentopyranose, 1,3,4-tris-O-(trimethylsilyl)-; 1,3,4-Tri-O-trimethylsilyl-2-deoxy-D-erythro-pentopyranose; 2-Deoxy-1,3,4-tri-O-trimethylsilyl-D-erythro-pentopyranose; Tris-O-trimethylsilyl-2-deoxy-D-erythro-pentopyranose; Protected 2-deoxypentose; TMS-protected 2-deoxyribose derivative
EINECS	Contact for details

Quality Control

Our 1-O,3-O,4-o-Tris(Trimethylsilyl)-2-Deoxy-D-Erythro-Pentopyranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.