Description

(9Z,13E,15S)-9-(Methoxyimino)-15-(Trimethylsiloxy)Prosta-10,13-Dien-1-Oic Acid Trimethylsilyl Ester is a key synthetic intermediate in the production of prostaglandin analogs and other bioactive molecules. This compound matters for its role in enabling precise chemical transformations, offering researchers and manufacturers a protected, reactive building block for complex organic synthesis. It is primarily needed by pharmaceutical R&D teams and fine chemical producers focused on developing advanced therapeutics, particularly in the fields of ophthalmology and cardiovascular medicine.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research and production of prostaglandin analogs for glaucoma treatment (e.g., Latanoprost, Travoprost precursors).
• Organic Synthesis: Serves as a versatile intermediate in stereoselective synthesis and medicinal chemistry projects.
• Biochemical Research: Employed in studies investigating prostanoid receptor activity and signal transduction pathways.
• Fine Chemical Manufacturing: Utilized in the scaled-up production of high-value, complex chiral molecules.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(9Z,13E,15S)-9-(Methoxyimino)-15-(Trimethylsiloxy)Prosta-10,13-Dien-1-Oic Acid Trimethylsilyl Ester
CAS No.	56227-29-3
Molecular Formula	C27H49NO4Si2
Molecular Weight	507.86 g/mol
Synonyms	9-(Methoxyimino)-15-(trimethylsiloxy)prosta-10,13-dien-1-oic Acid Trimethylsilyl Ester; Prostaglandin F2α Trimethylsilyl Ether Oxime Methyl Ether; 9(E)-Methoxyimino-11,15-bis(trimethylsiloxy)-5-cis-13-trans-prostadienoic Acid Trimethylsilyl Ester; 15-(Trimethylsilyloxy)-9-[(methoxyimino)methyl]-5Z,13E-prostadienoic Acid Trimethylsilyl Ester; PG F2α TMS Oxime Methyl Ether; Latanoprost Intermediate; Fluprostenol Related Compound; Isopropyl (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oate Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Production follows GMP-like guidelines suitable for pharmaceutical intermediate applications, with strict in-process controls. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and light-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.