Description

2-Bromothiophene-3-Carbonitrile is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a bromine atom and a nitrile group on a thiophene scaffold, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene ring's bioactivity.
• Material Science: Acts as a monomer or building block for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Research: A valuable reagent for heterocyclic chemistry, facilitating cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to the electron-withdrawing nitrile group.

Basic Information

Product Name	2-Bromothiophene-3-Carbonitrile
CAS No.	56182-43-5
Molecular Formula	C5H2BrNS
Molecular Weight	187.04 g/mol
Synonyms	3-Cyano-2-bromothiophene; 2-Bromo-3-thiophenecarbonitrile; 2-Bromothiophene-3-carbonitrile; 2-Bromo-3-cyanothiophene; Thiophene-3-carbonitrile, 2-bromo-; 3-Thiophenecarbonitrile, 2-bromo-
EINECS	Contact for details

Quality Control

Our 2-Bromothiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.