Description

3-[1,1'-Biphenyl]-4-Yl-1,2,3,4-Tetrahydro-1-Naphthol is a specialized organic compound featuring a tetrahydro-naphthol core linked to a biphenyl moiety. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, including potential active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or with complex polycyclic architectures.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy.
• Liquid Crystal & OLED Material Research: Used in the development of organic electronic materials due to its rigid, conjugated biphenyl-naphthol structure which can influence charge transport and luminescent properties.
• Catalyst & Ligand Development: The phenolic and aromatic groups provide potential coordination sites for creating novel metal-organic catalysts or ligands for asymmetric synthesis.
• Polymer Modification: Can be incorporated as a functional monomer to impart specific thermal, optical, or mechanical properties to advanced polymeric materials.
• Academic & Contract Research: A critical reagent for methodological studies in organic synthesis, including cross-coupling reactions and cyclization strategies.

Basic Information

Product Name	3-[1,1'-Biphenyl]-4-Yl-1,2,3,4-Tetrahydro-1-Naphthol
CAS No.	56181-66-9
Molecular Formula	C23H20O
Molecular Weight	312.41 g/mol
Synonyms	3-(4-Phenylphenyl)-1,2,3,4-tetrahydro-1-naphthol; 1,2,3,4-Tetrahydro-3-(4-phenylphenyl)-1-naphthalenol; 3-(Biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthol; 3-(4-Biphenylyl)-1,2,3,4-tetrahydro-1-naphthol; 1-Naphthol, 3-(1,1'-biphenyl)-4-yl-1,2,3,4-tetrahydro-; 3-(4-Phenylphenyl)-1,2,3,4-tetrahydro-1-naphthalenol
EINECS	Contact for details

Quality Control

Our 3-[1,1'-Biphenyl]-4-Yl-1,2,3,4-Tetrahydro-1-Naphthol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific project needs, including compliance with cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.