Description

(5α,12β,19α,20R)-1,9-Diformyl-2α,20-Cyclo-8,9-Secoaspidospermidine-3α-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate derived from the aspidosperma alkaloid structural class. This compound matters as a critical building block in the synthesis of complex bioactive molecules, offering a defined stereochemistry essential for targeted drug development. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and production of novel therapeutic agents, particularly in oncology and neurological research.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific biological pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and studying novel chemical transformations.
• Alkaloid Chemistry Studies: Acts as a model compound or starting material for the semi-synthesis and structural modification of natural aspidosperma alkaloids.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new molecules with optimized pharmacological profiles.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(5α,12β,19α,20R)-1,9-Diformyl-2α,20-Cyclo-8,9-Secoaspidospermidine-3α-Carboxylic Acid Methyl Ester
CAS No.	56053-34-0
Molecular Formula	C23H26N2O5
Molecular Weight	410.47 g/mol
Synonyms	1,9-Diformyl-2α,20-cyclo-8,9-secoaspidospermidine-3α-carboxylic acid methyl ester; Methyl (5α,12β,19α,20R)-1,9-diformyl-2α,20-cyclo-8,9-secoaspidospermidine-3α-carboxylate; Secoaspidospermidine derivative; Aspidosperma alkaloid intermediate; 8,9-Secoaspidospermidine-3α-carboxylic acid methyl ester, 1,9-diformyl-2α,20-cyclo-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (5α,12β,19α,20R)-1,9-Diformyl-2α,20-Cyclo-8,9-Secoaspidospermidine-3α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.