Description

(E)-3-Isobutylidenephthalide is a specific stereoisomer of a phthalide derivative, a class of compounds known for their diverse biological activities and utility in organic synthesis. This high-purity intermediate is critical for researchers and manufacturers requiring precise chemical structures for developing new active ingredients. It serves as a valuable building block for the pharmaceutical, agrochemical, and fine chemical industries, particularly in projects involving flavor & fragrance development and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the research and development of novel therapeutic agents.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products.
• Flavor & Fragrance (F&F) Industry: Serves as a starting material for synthesizing complex aroma compounds and flavorants.
• Fine Chemical Production: Employed in multi-step organic syntheses to construct more complex molecular architectures.
• Academic & Industrial R&D: A standard compound for methodological studies in organic chemistry and catalysis.
• Chemical Reference Standard: Used for analytical method development, calibration, and quality control in related manufacturing processes.

Basic Information

Product Name	(E)-3-Isobutylidenephthalide
CAS No.	56014-69-8
Molecular Formula	C12H12O2
Molecular Weight	188.22 g/mol
Synonyms	(E)-3-(2-Methylpropylidene)-1(3H)-isobenzofuranone; (E)-3-Isobutylidene-1(3H)-isobenzofuranone; (E)-3-(2-Methylpropylidene)phthalide; 3-[(E)-2-Methylpropylidene]-1(3H)-isobenzofuranone; Ligustilide isomer; (E)-Ligustilide; Senkyunolide related compound; Phthalide derivative
EINECS	Contact for details

Quality Control

Our (E)-3-Isobutylidenephthalide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets exacting research and industrial-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.