Description

1-(2-Bromoethyl)Pyrrolidine-2,5-Dione is a versatile brominated heterocyclic building block, primarily valued for its reactive bromoethyl side chain attached to a pyrrolidine-2,5-dione (succinimide) core. This compound is essential for introducing functionalized alkyl chains into target molecules, enabling the synthesis of more complex structures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a functionalized ethyl linker.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Reagent: Serves as an alkylating agent in various organic transformations to construct complex molecular architectures.
• Bioconjugation & Linker Chemistry: Employed in the development of chemical probes, drug conjugates, and bioconjugation strategies due to its reactive halogen.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology: Useful for modifying proteins, peptides, or other biomolecules to study function or create novel biotherapeutics.

Basic Information

Product Name	1-(2-Bromoethyl)Pyrrolidine-2,5-Dione
CAS No.	55943-72-1
Molecular Formula	C6H8BrNO2
Molecular Weight	206.04 g/mol
Synonyms	N-(2-Bromoethyl)succinimide; 2-(2,5-Dioxopyrrolidin-1-yl)ethyl bromide; 1-(2-Bromoethyl)-2,5-pyrrolidinedione; Succinimide, N-(2-bromoethyl)-; N-2-Bromoethylsuccinimide; 2-Bromoethylsuccinimide; 1-(β-Bromoethyl)succinimide
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethyl)Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.