Description

1-Chloro-4-Fluorocyclohexane is a versatile halogenated cyclohexane derivative that serves as a valuable intermediate in advanced organic synthesis. Its unique structure, featuring both chlorine and fluorine substituents, makes it a critical building block for introducing specific functional groups and modifying molecular properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Polymer Modification Agent: Imparts specific chemical resistance and stability properties when incorporated into specialty polymer chains.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for complex molecule construction in R&D laboratories.
• Fluorine Chemistry Research: A standard substrate for studying the effects of fluorine substitution on conformational stability and reactivity in cyclohexane systems.

Basic Information

Product Name	1-Chloro-4-Fluorocyclohexane
CAS No.	55887-80-4
Molecular Formula	C6H10ClF
Molecular Weight	136.59 g/mol
Synonyms	4-Fluoro-1-chlorocyclohexane; Cyclohexane, 1-chloro-4-fluoro-; 1-Chloro-4-fluorocyclohexane; 4-Fluorocyclohexyl chloride; (4-Fluorocyclohexyl)chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Fluorocyclohexane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reactive metals. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Isomer Ratio (cis/trans)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.