Description

1-Chloro-3-Fluorocyclohexane is a versatile halogenated cycloalkane building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of chlorine and fluorine atoms on the cyclohexane ring, enabling precise structural modifications and the introduction of unique physicochemical properties into target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Acts as a foundational component in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and ring-opening polymerizations to construct complex molecular architectures.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in cycloaliphatic systems.
• Specialty Polymer Modifier: Incorporated to impart specific properties like altered solubility, thermal stability, or chemical resistance to polymeric materials.

Basic Information

Product Name	1-Chloro-3-Fluorocyclohexane
CAS No.	55887-79-1
Molecular Formula	C6H10ClF
Molecular Weight	136.59 g/mol
Synonyms	3-Fluoro-1-chlorocyclohexane; Cyclohexane, 1-chloro-3-fluoro-; 1-Chloro-3-fluorocyclohexane; 3-Fluorocyclohexyl chloride; (3-Fluorocyclohexyl)chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Fluorocyclohexane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.1 g/mL
Boiling Point	~150-155°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.