Description

1H-Indole-3-Acetic Acid, 5-Methoxy-1-(Trimethylsilyl)-, Trimethylsilyl Ester is a specialized, high-purity organosilicon derivative of a key indole acetic acid scaffold. This compound is engineered to offer enhanced stability and reactivity, making it a critical synthetic intermediate for advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel bioactive molecules, including potential plant growth regulators and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of next-generation plant growth regulators and herbicides due to its structural relation to auxin-like compounds.
• Organic Synthesis: Serves as a protected and silylated reagent for complex multi-step syntheses, particularly in heterocyclic and medicinal chemistry.
• Biochemical Research: Employed in studies investigating plant hormone pathways and signaling mechanisms.
• Material Science Precursor: Potential starting material for creating specialized silicon-containing organic frameworks or coatings.

Basic Information

Product Name	1H-Indole-3-Acetic Acid, 5-Methoxy-1-(Trimethylsilyl)-, Trimethylsilyl Ester
CAS No.	55887-55-3
Molecular Formula	C₁₇H₂₅NO₃Si₂
Molecular Weight	347.56 g/mol
Synonyms	5-Methoxy-1-(trimethylsilyl)-1H-indole-3-acetic acid trimethylsilyl ester; 1H-Indole-3-acetic acid, 5-methoxy-1-(trimethylsilyl)-, trimethylsilyl ester; 5-Methoxy-1-trimethylsilylindole-3-acetic acid TMS ester; TMS ester of 5-Methoxy-1-TMS-indole-3-acetic acid; 55887-55-3; 5-Methoxy-1-(trimethylsilyl)indole-3-ylacetic acid trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-3-Acetic Acid, 5-Methoxy-1-(Trimethylsilyl)-, Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as fluorides and strong alkalis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.