Description

Methyl Methanethiosulfonate-D3 CAS NO 55800-37-8 is a deuterated isotopologue of methyl methanethiosulfonate (MMTS), a versatile sulfur-containing reagent. This compound is specifically valued for its role as a stable isotope-labeled internal standard in quantitative mass spectrometry analysis, ensuring high accuracy and reliability in analytical measurements. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and life science sectors, where precise quantification of thiol-reactive compounds is critical.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the accurate quantification of methyl methanethiosulfonate and related thiol-modifying agents in complex biological and chemical matrices.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and metabolism studies to track and quantify drug candidates and their metabolites that interact with thiol groups.
• Proteomics & Biochemistry: Employed in studies of protein S-thiolation, cysteine modification, and redox signaling pathways, where isotopic labeling is required for precise measurement.
• Agrochemical Analysis: Facilitates the reliable detection and quantification of pesticide residues or active ingredients that undergo thiol-based reactions.
• Method Development & Validation: Essential for developing and validating robust analytical methods in compliance with guidelines from regulatory bodies like the FDA and EMA.
• Quality Control (QC) Laboratories: Provides a reference standard for ensuring batch-to-batch consistency and purity in the production of sulfur-containing chemicals.

Basic Information

Product Name	Methyl Methanethiosulfonate-D3
CAS No.	55800-37-8
Molecular Formula	C2D3HO2S2
Molecular Weight	127.19 g/mol
Synonyms	Deuterated Methyl Methanethiosulfonate; MMTS-d3; Methyl-d3 Methanesulfonothioate; (Methyl-d3)sulfonyl Thiomethane; S-Methyl Methanethiosulfonate-d3; Deuterated S-Methyl Methanethiosulfonate; Methyl-d3 Thiosulfonate; [2H3]Methyl Methanethiosulfonate
EINECS	Contact for details

Quality Control

Our Methyl Methanethiosulfonate-D3 is manufactured under strict quality management systems to ensure the highest isotopic and chemical purity. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and analytical results is provided with every shipment to support your research and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99.0 atom % D
Chemical Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.