Description

N,n-Dimethyl-1-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is a specialized organosilicon-protected indole derivative, serving as a critical advanced intermediate in complex organic syntheses. Its value lies in the dual trimethylsilyl (TMS) protecting groups, which shield reactive hydroxyl and amine functionalities, enabling precise, multi-step reactions in controlled environments. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals where selective deprotection strategies are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those with indole-based core structures.
• Agrochemical Research: Used in developing novel pesticides and herbicides that require sophisticated heterocyclic chemistry.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing intricate molecular architectures via protective group chemistry.
• Material Science Precursor: Potential use in synthesizing specialized organic semiconductors or ligands for catalytic systems.
• Process Chemistry: Serves as a high-value intermediate in scale-up and optimization studies for commercial production routes.

Basic Information

Item	Details
Product Name	N,n-Dimethyl-1-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine
CAS No.	55760-24-2
Molecular Formula	C18H32N2OSi2
Molecular Weight	348.64 g/mol
Synonyms	1H-Indole-3-ethanamine, N,N-dimethyl-1-(trimethylsilyl)-4-[(trimethylsilyl)oxy]-; 4-[(Trimethylsilyl)oxy]-1-(trimethylsilyl)-N,N-dimethyl-1H-indole-3-ethanamine; N,N-Dimethyl-2-[1-(trimethylsilyl)-4-(trimethylsilyloxy)-1H-indol-3-yl]ethanamine; 55760-24-2; Protected Serotonin Derivative; Bis-TMS Indole Amine
EINECS	Contact for details

Quality Control

Every batch of N,n-Dimethyl-1-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.