Description

Benzyl 2,5-Dihydro-2,5-Dioxo-1H-Pyrrole-1-Carboxylate is a versatile chemical intermediate featuring a reactive maleimide core protected by a benzyloxycarbonyl (Cbz) group. This compound is crucial for researchers and manufacturers requiring a protected, activated scaffold for the synthesis of complex molecules, particularly in pharmaceutical development. It is primarily utilized in organic synthesis and as a key building block for creating active pharmaceutical ingredients (APIs), advanced polymers, and specialty materials.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of maleimide-containing drug candidates and active pharmaceutical ingredients (APIs).
• Peptide & Protein Conjugation: Used in bioconjugation chemistry to attach payloads (e.g., drugs, dyes, polymers) to peptides, proteins, or antibodies via thiol-maleimide "click" chemistry.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating functional polymers, hydrogels, and smart materials with tailored properties.
• Organic Synthesis Building Block: Provides a versatile platform for constructing heterocyclic compounds, complex natural product analogs, and other specialty chemicals.
• Research & Development: Essential in academic and industrial R&D labs for exploring new synthetic routes and developing novel chemical entities.
• Agrochemical Synthesis: Used as an intermediate in the development of certain advanced crop protection agents.

Basic Information

Product Name	Benzyl 2,5-Dihydro-2,5-Dioxo-1H-Pyrrole-1-Carboxylate
CAS No.	55750-51-1
Molecular Formula	C12H9NO4
Molecular Weight	231.20 g/mol
Synonyms	1-(Benzyloxycarbonyl)pyrrole-2,5-dione; N-Cbz-Maleimide; Benzyl N-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)carbamate; 1-(Benzyloxycarbonyl)maleimide; Cbz-Maleimide; N-Carbobenzoxy-maleimide; Maleimide, N-carbobenzoxy-; 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2,5-dioxo-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 2,5-Dihydro-2,5-Dioxo-1H-Pyrrole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.