Description

3-(2-Aminoethyl)-5-Nitroindole is a specialized nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique bifunctional structure, featuring both a primary amine and a nitro group on the indole scaffold, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel bioactive molecules and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Organic Synthesis Building Block: Employed in the construction of more complex heterocyclic compounds, including fused ring systems, due to its reactive amine and nitro functionalities.
• Agrochemical Research: Serves as an intermediate in the development of novel crop protection agents and pesticides.
• Dye and Pigment Synthesis: Utilized in the research and development of specialized nitro-containing colorants and functional materials.
• Biochemical Probe Development: Acts as a starting material for creating molecular probes to study biological pathways and enzyme interactions.

Basic Information

Product Name	3-(2-Aminoethyl)-5-Nitroindole
CAS No.	55747-72-3
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	5-Nitro-3-(2-aminoethyl)indole; 3-(2-Aminoethyl)-5-nitro-1H-indole; 1H-Indole-3-ethanamine, 5-nitro-; 5-Nitroindole-3-ethylamine; 2-(5-Nitro-1H-indol-3-yl)ethan-1-amine; 3-(2-Aminoethyl)-5-nitroindole; 5-Nitro-1H-indole-3-ethanamine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 3-(2-Aminoethyl)-5-Nitroindole is analyzed to ensure high purity and consistency, with specifications typically covering identity, assay, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing the results of these tests is provided with every shipment and is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.