Description

(3β,20α)-11,17α-Dimethoxy-18β-[(3,5-Dimethoxy-4-Isopropylbenzoyl)Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester CAS NO 55729-39-0 is a complex yohimbane alkaloid derivative, a high-purity intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key synthetic precursor in the exploration of novel therapeutic agents targeting the central nervous system and other physiological pathways. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and academic institutions engaged in the synthesis of specialized alkaloid-based compounds for pharmacological studies.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex alkaloid derivatives for drug discovery programs.
• Neurological Research: Used as a precursor in the development of compounds for studying adrenergic and serotonergic receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the biological profile of yohimbane-related molecules.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and the study of natural product derivatives.
• Process Development: Acts as a key material for scaling up synthetic routes in process chemistry for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(3β,20α)-11,17α-Dimethoxy-18β-[(3,5-Dimethoxy-4-Isopropylbenzoyl)Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester
CAS No.	55729-39-0
Molecular Formula	C36H44N2O8
Molecular Weight	632.75 g/mol
Synonyms	Methyl 11,17α-dimethoxy-18β-[(3,5-dimethoxy-4-isopropylbenzoyl)oxy]yohimban-16β-carboxylate; 18β-Hydroxyyohimban-16β-carboxylic acid, 11,17-dimethoxy-, methyl ester, 4-isopropyl-3,5-dimethoxybenzoate (ester); Rescinnamine Impurity; Rescinnamine Related Compound; 3β,20α-Yohimban-16β-carboxylic acid, 11,17α-dimethoxy-18β-[(3,5-dimethoxy-4-isopropylbenzoyl)oxy]-, methyl ester; Methyl Rescinnamate Analog
EINECS	Contact for details

Quality Control

Our (3β,20α)-11,17α-Dimethoxy-18β-[(3,5-Dimethoxy-4-Isopropylbenzoyl)Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.