Description

1-Bromobutane-4,4,4-D3 is a deuterium-labeled isotopologue of 1-bromobutane, a valuable alkylating agent and synthetic intermediate. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry and NMR spectroscopy, providing unmatched accuracy in analytical research and method development. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise isotopic labeling for metabolic studies, reaction mechanism elucidation, and high-purity synthesis.

Application

• Internal Standard for Analytical Chemistry: Primary use as a quantitative reference standard in GC-MS, LC-MS, and NMR analysis for accurate measurement of 1-bromobutane and related compounds.
• Pharmaceutical Research & Development: Critical for drug metabolism and pharmacokinetics (DMPK) studies, enabling the tracking of metabolites in biological systems.
• Mechanistic Studies: Used as a labeled reagent to investigate reaction pathways and kinetics in organic synthesis and catalysis.
• Deuterated Building Block: Serves as a precursor for the synthesis of more complex deuterium-labeled molecules for specialized applications.
• Quality Control & Method Validation: Employed in analytical laboratories to validate testing methods and ensure regulatory compliance (e.g., FDA, ICH guidelines).
• Material Science Research: Used in the development and analysis of novel polymers or organic electronic materials where isotopic purity is a factor.

Basic Information

Product Name	1-Bromobutane-4,4,4-D3
CAS No.	55724-42-0
Molecular Formula	C4H6D3Br
Molecular Weight	138.01 g/mol (approx.)
Synonyms	Butyl-d3 Bromide; 4,4,4-Trideuterio-1-bromobutane; n-Butyl-d3 Bromide; 1-Bromo-4,4,4-trideuteriobutane; Deuterated n-Butyl Bromide; [2H3]-1-Bromobutane; Butane-1,1,1-d3, 1-bromo-
EINECS	Contact for details

Quality Control

Every batch of 1-Bromobutane-4,4,4-D3 is produced and tested under stringent quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive analysis via NMR, GC-MS, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically >98% chemical purity, >99 atom % D), and impurity profile. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 99 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.