Description

1-Bromobutane-2,2-D2 is a deuterium-labeled analog of 1-bromobutane, a valuable alkylating agent and synthetic intermediate. This isotopically labeled compound is essential for mechanistic studies, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry, providing critical insights without interfering with natural isotopic abundances. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for deuterium incorporation and analytical applications.

Application

• Deuterium Labeling in Pharmaceutical R&D: Used as a deuterium source in the synthesis of deuterated drug candidates to study pharmacokinetics, metabolic stability, and bioavailability.
• Mechanistic Reaction Studies: Serves as a tracer in organic synthesis to elucidate reaction mechanisms and pathways in catalytic processes.
• Internal Standard for Analytical Chemistry: Employed as a high-purity standard in GC-MS and LC-MS for the accurate quantification of 1-bromobutane and related compounds.
• Synthesis of Specialty Materials: Acts as a building block for creating deuterated polymers, liquid crystals, or other advanced materials where isotopic purity affects physical properties.
• NMR Spectroscopy Solvent & Reagent: Useful in nuclear magnetic resonance (NMR) spectroscopy as a reagent or in solvent systems where deuterium labeling is required.

Basic Information

Product Name	1-Bromobutane-2,2-D2
CAS No.	55724-40-8
Molecular Formula	C4H7D2Br
Molecular Weight	138.01 g/mol (approx.)
Synonyms	Butyl-2,2-d2 bromide; 1-Bromo-2,2-dideuteriobutane; 2,2-Dideuterio-1-bromobutane; n-Butyl-2,2-d2 bromide; Deuterated 1-bromobutane; [2,2-2H2]1-Bromobutane; 55724-40-8 (CAS); Butane-2,2-d2, 1-bromo-
EINECS	Contact for details

Quality Control

Our 1-Bromobutane-2,2-D2 is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for research and analytical applications. Each batch is characterized by NMR, GC-MS, and IR spectroscopy to confirm structure, deuterium incorporation, and purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. For long-term storage, consider keeping under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.