Description

2,3,5,6-Tetrahydro-5-(1H-Indol-3-Yl)-3-Methyl-1H-Pyrrolo[2,1-B][1,3]Benzodiazepine is a complex heterocyclic compound belonging to the benzodiazepine class, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate fused-ring structure makes it a valuable scaffold for synthesizing novel therapeutic agents targeting the central nervous system. This high-purity compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities with potential biological activity.
• Neurological & Psychiatric Drug Development: Serves as a precursor in research targeting receptors in the central nervous system for potential anxiolytic, sedative, or other neuroactive properties.
• Biochemical Research: Employed in studies investigating ligand-receptor interactions and the modulation of specific neurotransmitter systems.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	2,3,5,6-Tetrahydro-5-(1H-Indol-3-Yl)-3-Methyl-1H-Pyrrolo[2,1-B][1,3]Benzodiazepine
CAS No.	55683-07-3
Molecular Formula	C22H21N3
Molecular Weight	327.43 g/mol
Synonyms	3-Methyl-5-(1H-indol-3-yl)-1H,2H,3H,5H,6H-pyrrolo[2,1-b][1,3]benzodiazepine; 5-(1H-Indol-3-yl)-3-methyl-2,3,5,6-tetrahydro-1H-pyrrolo[2,1-b][1,3]benzodiazepine; Pyrrolobenzodiazepine Indole Derivative; PBD-Indole Hybrid; Tricyclic Benzodiazepine Intermediate
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrahydro-5-(1H-Indol-3-Yl)-3-Methyl-1H-Pyrrolo[2,1-B][1,3]Benzodiazepine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.