Description

2-[Bis(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester is a highly functionalized organosilicon compound, valued for its role as a versatile silylating agent and protected amino acid derivative in advanced synthetic chemistry. Its primary commercial value lies in enabling complex organic transformations, particularly in the synthesis of peptides and other bioactive molecules, by providing robust protection for sensitive functional groups. This specialty chemical is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials sectors where precise molecular construction is critical.

Application

• Peptide Synthesis: Used as a key building block and protecting group reagent for amino acids in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a critical intermediate in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Employed in the research and production of novel pesticides and herbicides requiring specialized silicon-containing motifs.
• Organosilicon Chemistry: Acts as a precursor for the introduction of the bis(trimethylsilyl)amino (BTMSA) group into target molecules.
• Material Science Research: Utilized in the development of novel silicon-based polymers and hybrid organic-inorganic materials.
• Chemical Derivatization: Functions as a derivatization agent in analytical chemistry for gas chromatography (GC) and mass spectrometry (MS) to enhance volatility and detectability of polar compounds.

Basic Information

Item	Detail
Product Name	2-[Bis(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester
CAS No.	55649-90-6
Molecular Formula	C13H33NO2Si3
Molecular Weight	319.67 g/mol
Synonyms	2-[Bis(trimethylsilyl)amino]butyric acid trimethylsilyl ester; N,N-Bis(trimethylsilyl)-2-aminobutyric acid trimethylsilyl ester; 2-(Bis(trimethylsilyl)amino)butanoic acid trimethylsilyl ester; BTMS-2-Aminobutyrate TMS Ester; (Trimethylsilyl) 2-[bis(trimethylsilyl)amino]butanoate
EINECS	Contact for details

Quality Control

Our production of 2-[Bis(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All materials are characterized using advanced analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.