Description

1,2,3,4-Tetrahydro-2-(Trifluoroacetyl)Isoquinoline CAS NO 55649-51-9 is a specialized heterocyclic building block featuring a fused isoquinoline core modified with a trifluoroacetyl group. This compound is valued for its unique chemical reactivity and structural features, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the stability of the trifluoromethyl group.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals and specialty polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and methodological studies for constructing complex nitrogen-containing heterocycles.
• Fluorine Chemistry: An important reagent for introducing the trifluoroacetyl moiety into target molecules, enhancing their metabolic stability and lipophilicity.

Basic Information

Product Name	1,2,3,4-Tetrahydro-2-(Trifluoroacetyl)Isoquinoline
CAS No.	55649-51-9
Molecular Formula	C₁₁H₁₀F₃NO
Molecular Weight	229.20 g/mol
Synonyms	2-(Trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(trifluoroacetyl)isoquinoline; 2-Trifluoroacetyl-1,2,3,4-tetrahydroisoquinoline; N-(Trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-2-carboxylic acid trifluoromethyl ketone; TFATIQ; 55649-51-9
EINECS	Contact for details

Quality Control

Our production of 1,2,3,4-Tetrahydro-2-(Trifluoroacetyl)Isoquinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.