Description

n-(Tetrahydro-2H-Pyran-2-Yloxy)Succinimide is a versatile chemical intermediate, primarily recognized for its role as a protected hydroxylamine derivative. This compound is crucial for facilitating controlled synthetic transformations, particularly in the construction of complex molecules where selective functional group manipulation is required. It is an essential building block for researchers and manufacturers in the pharmaceutical and fine chemical industries engaged in advanced organic synthesis and API development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing N-O linked functional groups.
• Peptide Synthesis: Used as a reagent for the introduction of protected hydroxylamine functionalities during solid-phase and solution-phase peptide synthesis.
• Heterocyclic Chemistry: Serves as a valuable building block for the construction of various nitrogen- and oxygen-containing heterocyclic scaffolds.
• Linker Chemistry: Employed in the development of cleavable linkers for combinatorial chemistry and bioconjugation applications.
• Agrochemical Research: Utilized as an intermediate in the research and development of novel crop protection agents and herbicides.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for modifying polymer properties.

Basic Information

Product Name	n-(Tetrahydro-2H-Pyran-2-Yloxy)Succinimide
CAS No.	55610-40-7
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	N-(Tetrahydro-2H-pyran-2-yloxy)succinimide; 1-[(Tetrahydro-2H-pyran-2-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(tetrahydro-2H-pyran-2-yl)oxy]-; THP-ONSu; THP-OxySuccinimide; N-(THP-oxy)succinimide; N-(Tetrahydro-2-pyranyloxy)succinimide; O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine succinimidyl ester
EINECS	Contact for details

Quality Control

Our n-(Tetrahydro-2H-Pyran-2-Yloxy)Succinimide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with every shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.