Description

3-Methyl-3-[(Trimethylsilyl)Oxy]Glutaric Acid Bis(Trimethylsilyl) Ester is a highly functionalized, silyl-protected derivative of glutaric acid, serving as a versatile and protected synthetic intermediate. Its primary value lies in enabling complex organic syntheses where sensitive functional groups require protection from harsh reaction conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected dicarboxylic acid component in the synthesis of peptide analogs and mimetics.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialized polyesters and polyamides with tailored properties.
• Organic Synthesis Reagent: Provides a masked carboxylic acid functionality for use in nucleophilic substitution, condensation, and cyclization reactions.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct chiral centers, useful for producing enantiomerically pure compounds.
• Material Science Research: Investigated for creating novel silicon-containing hybrid organic-inorganic materials.

Basic Information

Product Name	3-Methyl-3-[(Trimethylsilyl)Oxy]Glutaric Acid Bis(Trimethylsilyl) Ester
CAS No.	55590-95-9
Molecular Formula	C15H34O5Si3
Molecular Weight	378.68 g/mol
Synonyms	3-Methyl-3-(trimethylsiloxy)glutaric acid bis(trimethylsilyl) ester; Glutaric acid, 3-methyl-3-[(trimethylsilyl)oxy]-, bis(trimethylsilyl) ester; 3-Methyl-3-trimethylsiloxyglutaric acid bis(trimethylsilyl) ester; TMS-protected 3-methyl-3-hydroxyglutarate; Bis(trimethylsilyl) 3-methyl-3-(trimethylsiloxy)glutarate; 3-Hydroxy-3-methylglutaric acid tris(trimethylsilyl) ether; Tris-O-TMS derivative of 3-hydroxy-3-methylglutaric acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-3-[(Trimethylsilyl)Oxy]Glutaric Acid Bis(Trimethylsilyl) Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.