Description

2-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Trimethyl Ester is a specialized organosilicon derivative of citric acid, serving as a versatile intermediate and protecting group reagent in advanced organic synthesis. Its unique structure, featuring both silyl ether and ester functionalities, makes it a valuable building block for modifying molecule polarity and stability. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical sectors, where precise molecular engineering is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring silyl-protected carboxylic acid groups.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its modified citric acid backbone can contribute to chelating properties or act as a synthetic handle.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored surface properties or biodegradability.
• Fine Chemical Production: Employed as a protected form of citric acid for complex multi-step organic syntheses, preventing unwanted side reactions at specific carboxyl sites.
• Silicon Chemistry Research: A valuable reagent for studying silylation reactions and the properties of silicon-containing organic molecules.
• Cosmetic Ingredient Intermediate: Potential use in synthesizing novel silicone-based esters for personal care formulations.

Basic Information

Product Name	2-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Trimethyl Ester
CAS No.	55590-87-9
Molecular Formula	C12H22O8Si
Molecular Weight	322.39 g/mol
Synonyms	Trimethyl 2-(trimethylsilyloxy)-1,2,3-propanetricarboxylate; 1,2,3-Propanetricarboxylic acid, 2-(trimethylsiloxy)-, trimethyl ester; Citric acid trimethyl ester 2-(trimethylsilyl) ether; 2-(Trimethylsiloxy)trimethyl citrate; Trimethyl O-(trimethylsilyl)citrate; TMS-Citrate trimethyl ester; Silylated trimethyl citrate
EINECS	Contact for details

Quality Control

Our production of 2-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Trimethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can lead to hydrolysis. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.