Description

2-[(Trimethylsilyl)Amino]-3-O,4-O,5-o-Tris(Trimethylsilyl)-2-Deoxy-D-Glucose 6-[Phosphoric Acid Bis(Trimethylsilyl)] Ester is a highly functionalized, fully silylated carbohydrate derivative, primarily used as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. Its value lies in providing a stable, reactive platform for the selective manipulation of sugar hydroxyl and amino groups, enabling the construction of complex glycoconjugates and nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel antiviral agents, carbohydrate-based therapeutics, and sophisticated chemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of modified nucleosides and nucleotide analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Serves as a protected precursor for the controlled, stepwise synthesis of complex oligosaccharides and glycoconjugates.
• Chemical Biology Tool: Used in the development of labeled sugar derivatives for metabolic pathway studies and imaging applications.
• Process Chemistry: Enables scalable routes to specialty carbohydrates where selective protection and deprotection strategies are required.
• Protecting Group Reagent: The multiple trimethylsilyl (TMS) groups act as temporary protecting agents for sensitive functional groups during multi-step syntheses.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related compounds.

Basic Information

Product Name	2-[(Trimethylsilyl)Amino]-3-O,4-O,5-o-Tris(Trimethylsilyl)-2-Deoxy-D-Glucose 6-[Phosphoric Acid Bis(Trimethylsilyl)] Ester
CAS No.	55530-82-0
Molecular Formula	C27H68NO9PSi6
Molecular Weight	771.41 g/mol
Synonyms	Per-O-trimethylsilyl 2-deoxy-2-(trimethylsilylamino)-D-glucose 6-phosphate; 2-Deoxy-2-(trimethylsilylamino)-D-glucose 3,4,5,6-tetrakis-O-(trimethylsilyl) 6-(bis(trimethylsilyl) phosphate); TMS-Protected 2-Amino-2-deoxy-D-glucose 6-Phosphate; Hexakis(trimethylsilyl) 2-Amino-2-deoxy-D-glucopyranose 6-Phosphate; Fully Silylated D-Glucosamine 6-Phosphate Derivative; 2-Amino-2-deoxy-D-glucose-3,4,5,6-tetra-O-trimethylsilyl-2-N-trimethylsilyl-6-O-bis(trimethylsilyl) phosphate
EINECS	Contact for details

Quality Control

Every batch of 2-[(Trimethylsilyl)Amino]-3-O,4-O,5-o-Tris(Trimethylsilyl)-2-Deoxy-D-Glucose 6-[Phosphoric Acid Bis(Trimethylsilyl)] Ester is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically assessed via NMR, HPLC, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and process development in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.