Description

2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-o-[Bis(Trimethylsilyloxy)Phosphinyl]-D-Mannose o-Methyl Oxime is a highly functionalized, silyl-protected carbohydrate derivative containing a phosphinyl group. This compound matters as a sophisticated chemical intermediate and building block for advanced organic synthesis, particularly in the development of complex bioactive molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for creating novel nucleoside analogs, glycoconjugates, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleosides, nucleotides, and carbohydrate-based drug candidates.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides and glycopeptides for biological studies and therapeutic applications.
• Agrochemical Research: Serves as a precursor for novel plant growth regulators or pesticide formulations with specific carbohydrate motifs.
• Chemical Biology Probes: Enables the creation of labeled or tagged sugar derivatives for studying enzymatic pathways and carbohydrate-protein interactions.
• Process Chemistry: Acts as a protected and activated intermediate in multi-step synthetic routes for scale-up production.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry and carbohydrate chemistry.

Basic Information

Product Name	2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-o-[Bis(Trimethylsilyloxy)Phosphinyl]-D-Mannose o-Methyl Oxime
CAS No.	55530-76-2
Molecular Formula	C27H67NO10PSi6
Molecular Weight	~782.4 g/mol
Synonyms	D-Mannose, 2,3,4,5-tetrakis-O-(trimethylsilyl)-6-O-[bis(trimethylsilyloxy)phosphinyl]-, O-methyloxime; 6-O-[Bis(trimethylsilyloxy)phosphinyl]-2,3,4,5-tetrakis-O-(trimethylsilyl)-D-mannose O-methyloxime; Tetrakis-O-TMS Mannose Phosphinyl Methyl Oxime; Silylated Mannose Phosphonate Oxime; TMS-protected Mannose Derivative; Carbohydrate Phosphonate Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C, ³¹P), HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system for consistent production of high-purity research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.