Description

2-[(Trimethylsilyl)Oxy]Pentanedioic Acid Bis(Trimethylsilyl) Ester is a specialized organosilicon derivative of glutaric acid, serving as a key protected intermediate in advanced organic synthesis. Its primary value lies in its dual functionality, offering both a silyl-protected hydroxyl group and silyl ester groups, which are highly volatile and reactive under controlled conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise protection and activation strategies for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring protected carboxylic acid and alcohol functionalities.
• Peptide & Nucleotide Chemistry: Acts as a protecting group reagent for glutamic acid derivatives and other bifunctional molecules during solid-phase and solution-phase synthesis.
• Agrochemical Synthesis: Serves as a building block for creating complex molecules with specific biological activity in crop protection agents.
• Polymer & Material Science: Utilized as a monomer or cross-linking agent in the development of specialty silicones and functional polymers.
• Chemical Derivatization for Analysis: Employed in Gas Chromatography (GC) and Mass Spectrometry (MS) to volatilize and analyze polar organic acids.
• Laboratory Reagent: A valuable tool for academic and industrial R&D focused on novel synthetic methodologies involving silicon chemistry.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]Pentanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	55530-62-6
Molecular Formula	C14H32O5Si3
Molecular Weight	364.66 g/mol
Synonyms	Glutaric Acid 2-(Trimethylsiloxy)-, Bis(trimethylsilyl) Ester; 2-(Trimethylsiloxy)pentanedioic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) 2-(trimethylsiloxy)pentanedioate; Glutaric Acid, 2-(Trimethylsiloxy)-, 1,5-Bis(trimethylsilyl) Ester; TMS-Glutarate Derivative; 55530-62-6; 2-(Trimethylsilyloxy)glutaric Acid Bis(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our production of 2-[(Trimethylsilyl)Oxy]Pentanedioic Acid Bis(Trimethylsilyl) Ester adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature and sensitivity to strong bases and moisture, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.