Description

17β-Hydroxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate or reference standard for developing novel bioactive molecules targeting the central nervous system. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and potential therapeutic agents. Our supply is characterized by stringent quality control, ensuring batch-to-batch consistency for reliable experimental and process-scale outcomes.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel alkaloid-based pharmaceuticals and investigational new drugs.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies aimed at discovering new neuroactive or receptor-targeting compounds.
• Process Chemistry: Intermediate in the scale-up and optimization of synthetic routes for complex natural product derivatives.
• Academic Research: Used in university and institutional labs for studying synthetic methodologies, reaction mechanisms, and the properties of yohimbane-related alkaloids.
• Biochemical Tool Compound: Potential use in pharmacological assays to study interactions with specific biological targets and pathways.

Basic Information

Product Name	17β-Hydroxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester
CAS No.	55529-55-0
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	Methyl 17β-hydroxy-19α-methyl-18-oxayohimban-16α-carboxylate; 18-Oxa-3,20-didehydroyohimban-16α-carboxylic acid, 17β-hydroxy-19α-methyl-, methyl ester; 19α-Methyl-18-oxayohimban-16α-carboxylic acid methyl ester, 17β-hydroxy-; Yohimbane alkaloid derivative; Oxayohimban derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 17β-Hydroxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester is produced and analyzed under a strict quality management system. We employ advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to ensure identity, purity, and conformity to client specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.