Description

1,3,4-Tris(Trimethylsilyl)-D-Threo-2-Pentulose 5-Phosphoric Acid Bis(Trimethylsilyl) Ester is a highly specialized, silyl-protected carbohydrate derivative that serves as a critical synthetic intermediate. Its value lies in enabling complex organic syntheses, particularly in the development of nucleoside analogs and other bioactive molecules where precise stereochemistry and functional group protection are paramount. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for sophisticated R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Carbohydrate Chemistry Research: Used as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents that require specific chiral centers.
• Process Chemistry & Scale-Up: Enables the reliable, multi-step synthesis of target molecules in pilot plant and commercial manufacturing.
• Bioconjugation & Probe Development: Serves as a precursor for labeled sugars used in biochemical assays and diagnostic imaging agents.
• Academic & Institutional R&D: Fundamental research tool in organic chemistry and medicinal chemistry laboratories for method development.

Basic Information

Product Name	1,3,4-Tris(Trimethylsilyl)-D-Threo-2-Pentulose 5-Phosphoric Acid Bis(Trimethylsilyl) Ester
CAS No.	55520-85-9
Molecular Formula	C20H51O8PSi5
Molecular Weight	603.10 g/mol
Synonyms	D-Threo-2-Pentulose, 1,3,4-tris-O-(trimethylsilyl)-, 5-(bis(trimethylsilyl) phosphate); 1,3,4-Tris-O-(trimethylsilyl)-D-threo-pentulose 5-(bis(trimethylsilyl) phosphate); Silylated D-Threo-2-Pentulose Phosphate Ester; TMS-Protected Pentulose Phosphate; CAS 55520-85-9
EINECS	Contact for details

Quality Control

Every batch of 1,3,4-Tris(Trimethylsilyl)-D-Threo-2-Pentulose 5-Phosphoric Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.