Description

Malonic Acid-2-13C is a stable isotope-labeled derivative of malonic acid, where the carbon atom at the 2-position is the carbon-13 (13C) isotope. This high-purity labeled compound is essential for applications requiring precise metabolic pathway tracing and internal standards in quantitative mass spectrometry. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors developing and analyzing new compounds.

Application

• Internal Standard for Quantitative Analysis: Used as a certified reference material in LC-MS and GC-MS for the accurate quantification of malonic acid and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Employed in 13C-NMR spectroscopy and isotope-ratio mass spectrometry to study the citric acid cycle, fatty acid synthesis, and other biochemical pathways.
• Pharmaceutical Research & Development: Serves as a labeled precursor or intermediate in the synthesis of isotopically labeled drug candidates for pharmacokinetic and metabolic stability studies.
• Environmental & Food Science: Applied in research to trace metabolic processes in plants, soil microbes, and in food authenticity testing.
• Chemical Synthesis: Utilized in the preparation of other 13C-labeled fine chemicals and building blocks for specialized research applications.

Basic Information

Product Name	Malonic Acid-2-13C
CAS No.	55514-11-9
Molecular Formula	C213CH4O4 or HOOC-13CH2-COOH
Molecular Weight	105.05 g/mol
Synonyms	Propanedioic Acid-2-13C; 1,3-Propanedioic Acid-2-13C; Carboxyacetic Acid-2-13C; Methanedicarboxylic Acid-2-13C; Dicarboxymethane-2-13C; 13C-Labeled Malonic Acid; Malonic-2-13C Acid; [2-13C]Malonic Acid
EINECS	Contact for details

Quality Control

Our Malonic Acid-2-13C is manufactured under strict quality control protocols to ensure high chemical and isotopic purity suitable for advanced research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay (by HPLC or titration), isotopic enrichment (by NMR or MS), and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.