Description

1-(4-Fluoro-Phenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a structurally defined scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs targeting neurological and cardiovascular disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules requiring the tetrahydroisoquinoline pharmacophore.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Investigated for its potential biological activity and interaction with various enzyme systems in academic and industrial research settings.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	55507-14-7
Molecular Formula	C17H18FNO2
Molecular Weight	287.33 g/mol
Synonyms	1-(4-Fluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline; 1-(4-Fluorophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline; 55507-14-7; 1-(p-Fluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-(p-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.