Description

Methyl-13C,D1 Iodide is a stable isotope-labeled derivative of methyl iodide, specifically enriched with carbon-13 and deuterium. This compound is essential for advanced analytical and synthetic chemistry, providing a non-radioactive tracer for precise metabolic, mechanistic, and pharmacokinetic studies. It is a critical reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and academic sectors who require high-fidelity isotopic labeling to track molecular pathways and synthesize labeled target compounds.

Application

• Pharmaceutical Research & Development: Used as a key methylating agent with isotopic labels for synthesizing drug metabolites and active pharmaceutical ingredients (APIs) in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry & Mass Spectrometry: Serves as an internal standard or a derivatization agent in quantitative methods like LC-MS and GC-MS, enhancing accuracy and detection sensitivity for target analytes.
• Metabolic Pathway Tracing: Employed in biochemical research to elucidate complex metabolic pathways and mechanisms in biological systems using carbon-13 and deuterium as tracers.
• Agrochemical Development: Utilized in the synthesis of isotopically labeled pesticides, herbicides, or their metabolites for environmental fate studies and regulatory compliance testing.
• NMR Spectroscopy: Acts as a precursor or reference compound in nuclear magnetic resonance (NMR) spectroscopy, aiding in structural elucidation and method development.
• Organic Synthesis: Provides a labeled methyl source for sophisticated organic synthesis, enabling the preparation of complex, isotopically enriched molecules for various research applications.

Basic Information

Product Name	Methyl-13C,D1 Iodide
CAS No.	55487-75-7
Molecular Formula	13CH3D I
Molecular Weight	144.94 g/mol (approx.)
Synonyms	Iodo-13C,d1-methane; (13C)Methyl-d1 Iodide; Deuterated Carbon-13 Methyl Iodide; Methyl-13C,d1 Iodide; 13CH3D I; Methyl-d1 Iodide-13C; Iodomethane-13C,d1; Methyl Iodide-13C,d1
EINECS	Contact for details

Quality Control

Our Methyl-13C,D1 Iodide is manufactured under stringent conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR, GC-MS, and HPLC, to verify isotopic enrichment, chemical purity, and identity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research and quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at 2-8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile and light-sensitive nature, containers should be kept sealed and allowed to equilibrate to room temperature before opening to prevent moisture ingress and pressure buildup.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (D)	≥ 98 atom %
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.