Description

1H-Pyrrolo[2,3-b]pyridin-6-amine, 2-methyl- is a high-purity heterocyclic amine building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical scaffold for developing novel pharmaceutical agents, particularly in kinase inhibitor research and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Organic Synthesis Building Block: Used to construct complex heterocyclic systems in medicinal chemistry and agrochemical research.
• Research & Development: Employed in academic and industrial labs for exploring new chemical entities and structure-activity relationships (SAR).
• Fine Chemical Production: Serves as a starting material for the manufacture of specialty chemicals requiring the 2-methyl-7-azaindole core structure.
• Biochemical Probe Development: Utilized in creating molecular tools for studying biological pathways and enzyme functions.

Basic Information

Product Name	1H-Pyrrolo[2,3-b]pyridin-6-amine, 2-methyl-
CAS No.	55463-64-4
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	2-Methyl-7-azaindol-6-amine; 2-Methyl-1H-pyrrolo[2,3-b]pyridin-6-amine; 6-Amino-2-methyl-1H-pyrrolo[2,3-b]pyridine; 2-Methyl-6-amino-7-azaindole; 2-Methyl-1H-pyrrolo[2,3-b]pyridin-6-ylamine; 2-Methyl-6-aminopyrrolo[2,3-b]pyridine; 2-Methyl-1,7-dideazapurine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-b]pyridin-6-amine, 2-methyl- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.