Description

3-(Trifluoromethyl)-1H-Indazole is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique indazole core substituted with a trifluoromethyl group makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Serves as a building block for advanced organic materials, including liquid crystals and organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for probe and tool compound development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	3-(Trifluoromethyl)-1H-Indazole
CAS No.	55440-17-0
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	1H-Indazole, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)indazole; 3-Trifluoromethyl-1H-indazole; 3-Trifluoromethylindazole; 55440-17-0; 3-CF3-1H-Indazole; 3-(Trifluoromethyl)indazole; 3-Trifluoromethyl-1H-indazole
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Observe all local regulations for the storage of industrial chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.