Description

Isopropyl-D6-Amine is a deuterated isotopologue of isopropylamine, where all six hydrogen atoms on the two methyl groups are replaced with deuterium. This high level of deuteration makes it an essential internal standard and tracer in advanced analytical chemistry, particularly for mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for metabolic studies, reaction mechanism elucidation, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Mass Spectrometry (MS): Provides precise quantification in GC-MS and LC-MS analyses due to its distinct mass shift, minimizing matrix effects.
• NMR Spectroscopy Solvent & Tracer: Used as a non-interfering deuterated solvent or a mechanistic tracer in reaction studies to track molecular pathways.
• Deuterated Pharmaceutical Intermediate: A key building block in the synthesis of deuterium-labeled drug candidates to enhance metabolic stability and pharmacokinetic profiles.
• Agrochemical Research: Employed in the development and analysis of deuterated pesticides and herbicides for studying environmental fate and metabolism.
• Organic Synthesis & Catalysis Research: Serves as a deuterium source or a labeled reagent in catalytic reactions and synthetic methodology development.
• Material Science: Used in the surface modification and synthesis of specialty polymers and coatings where deuterium labeling is required for analysis.

Basic Information

Product Name	Isopropyl-D6-Amine
CAS No.	55432-59-2
Molecular Formula	C3D9N
Molecular Weight	68.15 g/mol
Synonyms	2-Aminopropane-d6; (CD3)2CDND2; 2-Propanamine-d6; Isopropylamine-d6; Deutero-isopropylamine; Isopropylamine (hexadeutero); 1-Methylethylamine-d6; 2-Deuteroaminopropane-d5
EINECS	Contact for details

Quality Control

Every batch of Isopropyl-D6-Amine is produced and tested under stringent quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our standard specification includes verification of deuteration degree (typically >98 atom % D) and chemical purity (by GC) to meet the exacting requirements of research and development. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and strong alkali/organic solvent nature, keep away from heat, sparks, open flames, and strong oxidizing agents. Use appropriate grounding procedures during handling to prevent static discharge.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Deuteration Degree (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.