Description

1,3-Bis[(Trimethylsilyl)Oxy]-2-Propanone o-[Bis[(Trimethylsilyl)Oxy]Phosphinyl]Oxime is a specialized organosilicon reagent featuring a unique oxime phosphate structure. This compound is valued for its role as a versatile protecting group and intermediate in complex organic synthesis, particularly for sensitive functional groups. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing advanced active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring selective protection of hydroxyl or carbonyl groups.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its functional groups enable specific chemical transformations.
• Organosilicon Chemistry: Serves as a precursor or reagent in the development of novel silicon-containing compounds for material science applications.
• Peptide & Nucleotide Chemistry: Employed in the protection of sensitive intermediates during the synthesis of peptides, nucleotides, and their analogs.
• Cross-Coupling Reactions: Acts as a specialized ligand or additive in metal-catalyzed cross-coupling reactions to improve yield or selectivity.
• Academic & Industrial R&D: A valuable tool for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1,3-Bis[(Trimethylsilyl)Oxy]-2-Propanone o-[Bis[(Trimethylsilyl)Oxy]Phosphinyl]Oxime
CAS No.	55429-50-0
Molecular Formula	C12H32NO7PSi4
Molecular Weight	437.79 g/mol
Synonyms	1,3-Bis(trimethylsiloxy)-2-propanone O-[bis(trimethylsiloxy)phosphinyl]oxime; 2-Propanone, 1,3-bis[(trimethylsilyl)oxy]-, O-[bis[(trimethylsilyl)oxy]phosphinyl]oxime; Acetone O-(bis(trimethylsiloxy)phosphoryl)oxime bis(trimethylsilyl) acetal; TMS-protected acetone oxime phosphate; Bis(trimethylsilyl) Acetone Oxime Phosphate Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3-Bis[(Trimethylsilyl)Oxy]-2-Propanone o-[Bis[(Trimethylsilyl)Oxy]Phosphinyl]Oxime is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.