Description

2-[Bis(Trimethylsilyl)Amino]Ethyl Bis(Trimethylsilyl) Phosphate is a highly specialized organosilicon reagent featuring a unique bifunctional structure containing both silylamino and silyl phosphate groups. This compound is valued for its role as a versatile protecting group agent and a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on nucleoside chemistry, prodrug development, and the modification of sensitive bioactive compounds where selective protection of phosphate and amine functionalities is required.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nucleotide analogs and antiviral prodrugs.
• Protecting Group Reagent: Used for the simultaneous protection of phosphate and amine groups in complex multi-step organic syntheses.
• Agrochemical Research: Serves as an intermediate in the development of novel pesticides and herbicides with enhanced stability.
• Material Science: Potential precursor for modifying surface properties or creating silicon-containing polymers and coatings.
• Process Chemistry: Employed in scalable manufacturing processes for active pharmaceutical ingredients (APIs) requiring silyl protection strategies.

Basic Information

Item	Detail
Product Name	2-[Bis(Trimethylsilyl)Amino]Ethyl Bis(Trimethylsilyl) Phosphate
CAS No.	55334-92-4
Molecular Formula	C14H40N1O4P1Si4
Molecular Weight	426.81 g/mol
Synonyms	Bis(trimethylsilyl) 2-[bis(trimethylsilyl)amino]ethyl phosphate; 2-[Bis(trimethylsilyl)amino]ethyl di(trimethylsilyl) phosphate; N,N-Bis(trimethylsilyl)-2-aminoethyl bis(trimethylsilyl) phosphate; ATEP; Aminoethyl Tris(trimethylsilyl) Phosphate Derivative; Phosphoric acid, 2-[bis(trimethylsilyl)amino]ethyl ester, bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Every batch of 2-[Bis(Trimethylsilyl)Amino]Ethyl Bis(Trimethylsilyl) Phosphate is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical use, and we can accommodate custom purity requirements for specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.