Description

Phosphoric Acid, 2-(Methoxyimino)-3-[(Trimethylsilyl)Oxy]Propyl Bis(Trimethylsilyl) Ester is a specialized organosilicon-protected phosphoric acid derivative, designed for advanced synthetic applications where precise control over reactivity is paramount. This compound serves as a key reagent and protecting group in complex organic synthesis, particularly for the selective phosphorylation and modification of sensitive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for nucleotide analogs and other phosphate-containing therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the phosphoric acid moiety is a key functional group.
• Peptide & Nucleotide Chemistry: Acts as a phosphorylating agent and protecting group for hydroxyl functions in the synthesis of oligonucleotides and modified peptides.
• Material Science Research: Employed in the development of specialty polymers, surface modifiers, and ligands for catalysis that require silicon-protected phosphate groups.
• Process Chemistry: Utilized in scalable manufacturing processes for fine chemicals where the trimethylsilyl groups offer improved solubility and handling characteristics.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds and probes used to study biological phosphorylation pathways.

Basic Information

Product Name	Phosphoric Acid, 2-(Methoxyimino)-3-[(Trimethylsilyl)Oxy]Propyl Bis(Trimethylsilyl) Ester
CAS No.	55319-85-2
Molecular Formula	C15H38NO6PSi3
Molecular Weight	443.78 g/mol
Synonyms	2-(Methoxyimino)-3-[(trimethylsilyl)oxy]propyl bis(trimethylsilyl) phosphate; Phosphoric Acid Tris(trimethylsilyl) Glycidyl Ester Oxime Methyl Ether; (2-(Methoxyimino)-3-((trimethylsilyl)oxy)propyl) bis(trimethylsilyl) phosphate; Tris(trimethylsilyl) P-Glycidylphosphate Oxime Methyl Ether; TMS-Protected Phosphoglycidyl Oxime; Glycidyl Phosphate Tris(trimethylsilyl) Ester Oxime Methyl Ether; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our Phosphoric Acid, 2-(Methoxyimino)-3-[(Trimethylsilyl)Oxy]Propyl Bis(Trimethylsilyl) Ester is manufactured and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.