Description

Antrafenine Dihydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant importance in medicinal chemistry. Its value lies in its role as a key building block for the synthesis and development of novel therapeutic agents, particularly in the field of central nervous system (CNS) research. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for research and development.
• Medicinal Chemistry Research: Used as a building block for creating novel chemical entities and analogs in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in pharmacological studies to investigate receptor interactions and biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced chemical and pharmacological studies.

Basic Information

Product Name	Antrafenine Dihydrochloride
CAS No.	55300-30-6
Molecular Formula	C₂₀H₂₆Cl₂N₂O₂
Molecular Weight	397.34 g/mol
Synonyms	Antrafenine HCl; 1-[2-(Dimethylamino)ethyl]-N-(4-methoxyphenyl)-N-phenyl-1H-indazole-3-carboxamide dihydrochloride; 1-[2-(Dimethylamino)ethyl]-N-(4-methoxyphenyl)-N-phenylindazole-3-carboxamide dihydrochloride; Antrafenine 2HCl; Antrafenine Dihydrochloride Salt; Antrafenine Hydrochloride; Stablon Impurity
EINECS	Contact for details

Quality Control

Our Antrafenine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.