Description

Tiamulin Fumarate is a semi-synthetic pleuromutilin derivative antibiotic specifically designed for veterinary medicine. Its primary value lies in its potent activity against Gram-positive bacteria and mycoplasmas, making it a critical tool for maintaining animal health and productivity. This compound is essential for manufacturers in the animal health sector, particularly for producing premixes, water-soluble powders, and injectable solutions to treat and prevent respiratory and enteric diseases in swine and poultry.

Application

• Veterinary Pharmaceutical Formulations: Primary active ingredient in injectable solutions, oral powders, and premixes for swine and poultry.
• Treatment of Swine Dysentery: Specifically indicated for the control of swine dysentery associated with *Brachyspira hyodysenteriae*.
• Control of Mycoplasmal Pneumonia: Used in poultry and swine to combat respiratory infections caused by *Mycoplasma gallisepticum* and *Mycoplasma hyopneumoniae*.
• Growth Promotion & Prophylaxis: Incorporated into feed at sub-therapeutic levels to improve feed efficiency and prevent disease outbreaks in livestock.
• Aquaculture Applications: Investigated for use in controlling bacterial infections in farmed fish.
• Intermediate for Further Synthesis: Serves as a key starting material or intermediate in the synthesis of other pleuromutilin-based antibiotics.

Basic Information

Product Name	Tiamulin Fumarate
CAS No.	55297-96-6
Molecular Formula	C28H47NO8S • C4H4O4
Molecular Weight	609.73 g/mol
Synonyms	Tiamulin hydrogen fumarate; Dynamutilin; 14-Deoxy-14-[(2-diethylaminoethyl)mercaptoacetoxy]mutilin hydrogen fumarate; (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopentacycloocten-8-yl 2-[(diethylamino)ethylthio]acetate hydrogen fumarate; Tiamutin; Denagard (Veterinary Preparations)
EINECS	Contact for details

Quality Control

Our Tiamulin Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity standards suitable for veterinary pharmaceutical applications. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.