Description

Tiamulin CAS NO 55297-95-5 is a pleuromutilin derivative antibiotic primarily used in veterinary medicine. This compound is valued for its potent activity against Gram-positive bacteria and mycoplasmas, making it a critical tool for maintaining animal health and productivity. It is an essential active pharmaceutical ingredient (API) for manufacturers of veterinary pharmaceuticals targeting swine dysentery and poultry respiratory diseases.

Application

• Veterinary Pharmaceutical API: Primary use as the active ingredient in premixes, water-soluble powders, and injectable formulations for swine and poultry.
• Swine Health Management: Specifically indicated for the treatment and control of swine dysentery caused by *Brachyspira hyodysenteriae* and enzootic pneumonia.
• Poultry Health Management: Used for the treatment of chronic respiratory disease (CRD) in chickens and turkeys caused by *Mycoplasma gallisepticum*.
• Feed Additive Production: Incorporated into medicated feed to promote growth and prevent bacterial infections in livestock.
• Aquaculture: Investigational use for controlling bacterial infections in farmed fish, subject to regional regulatory approvals.
• Research & Development: Serves as a reference standard and key intermediate in antimicrobial research and new drug development.

Basic Information

Product Name	Tiamulin
CAS No.	55297-95-5
Molecular Formula	C28H47NO4S
Molecular Weight	493.75 g/mol
Synonyms	Tiamulin hydrogen fumarate; Tiamutin; Dynamutilin; 14-Deoxy-14-[(2-diethylaminoethyl)mercaptoacetoxy]mutilin hydrogen fumarate; Thiamutilin; (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopentacycloocten-8-yl 2-(diethylamino)ethanethioate hydrogen fumarate; Denagard® (Trade Name); Tiamutin® (Trade Name)
EINECS	259-564-1

Quality Control

Our Tiamulin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for veterinary pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.