Description

19,20-Dihydro-17-Hydroxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate or reference standard for the development of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Research: Employed in studies investigating the biological activity and mechanism of action of sarpagine-related alkaloids.
• Fine Chemical Synthesis: Utilized as a specialized reagent for the synthesis of other high-value, complex organic molecules in custom synthesis projects.

Basic Information

Item	Details
Product Name	19,20-Dihydro-17-Hydroxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester
CAS No.	55282-42-3
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Methyl 19,20-dihydro-17-hydroxy-1-methylsarpagan-16-carboxylate; 1-Methylsarpagine-16-carboxylic acid methyl ester, 19,20-dihydro-17-hydroxy-; 17-Hydroxy-19,20-dihydro-1-methylsarpagan-16-carboxylic acid methyl ester; Sarpagine derivative; Indole alkaloid intermediate; Alstonia scholaris alkaloid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 19,20-Dihydro-17-Hydroxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester is manufactured and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity assays and structural confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.