Description

3-Methoxy-6α-Methyl-17-(Phenylacetyl)Morphinan is a high-purity synthetic morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of specialized active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and analytical methods.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex opioid analgesics and related therapeutic compounds.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding affinity and structure-activity relationships (SAR) of morphinan derivatives.
• Process Chemistry: Serves as a starting material or intermediate in multi-step synthetic routes for the production of specialized APIs under controlled GMP environments.

Basic Information

Product Name	3-Methoxy-6α-Methyl-17-(Phenylacetyl)Morphinan
CAS No.	55281-49-7
Molecular Formula	C27H31NO3
Molecular Weight	417.54 g/mol
Synonyms	17-(Phenylacetyl)-3-methoxy-6α-methylmorphinan; 3-Methoxy-6α-methyl-17-(phenylacetyl)morphinan; 6α-Methyl-3-methoxy-17-(phenylacetyl)morphinan; 17-Phenylacetyl-3-methoxy-6α-methylmorphinan; 55281-49-7; Morphinan, 17-(phenylacetyl)-3-methoxy-6α-methyl-; 3-Methoxy-6α-methyl-17-(phenylacetyl)morphinan (non-preferred IUPAC)
EINECS	Contact for details

Quality Control

Our 3-Methoxy-6α-Methyl-17-(Phenylacetyl)Morphinan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.