Description

3-Methoxy-6α-Methyl-17-(2-Phenylethyl)Morphinan-14-Ol is a complex morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the study of opioid receptor pharmacology and the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs). The precise structure of this molecule makes it a valuable tool for exploring structure-activity relationships within its chemical class.

Application

• Pharmaceutical Research Intermediate: A key building block in the multi-step synthesis of novel opioid analgesics or receptor modulators.
• Reference Standard for Analytical Development: Used to develop and validate HPLC, GC-MS, or other analytical methods for quality control and impurity profiling.
• Medicinal Chemistry Studies: Employed in preclinical research to investigate pharmacological properties, metabolic pathways, and receptor binding affinities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Academic and Institutional Research: Used in university and government labs for fundamental studies in neurochemistry and pain management.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial compounds.

Basic Information

Product Name	3-Methoxy-6α-Methyl-17-(2-Phenylethyl)Morphinan-14-Ol
CAS No.	55268-49-0
Molecular Formula	C28H35NO2
Molecular Weight	417.59 g/mol
Synonyms	14-Hydroxy-3-methoxy-6α-methyl-17-(2-phenylethyl)morphinan; 17-(2-Phenylethyl)-3-methoxy-6α-methylmorphinan-14-ol; 6α-Methyl-17-(2-phenylethyl)-3-methoxymorphinan-14-ol; 3-Methoxy-6α-methyl-17-phenethylmorphinan-14-ol; Phenethylmorphinan derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity, essential for research reproducibility. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by validated analytical methods (e.g., HPLC, NMR). We operate under a quality management system and can supply material suitable for use under research-grade, GLP (Good Laboratory Practice), or cGMP frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.