Description

4-Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide is a high-purity, functionalized sulfolane derivative with significant synthetic utility. This compound serves as a versatile chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex heterocyclic and sulfone-based motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides that require specific stereochemistry and sulfone functionality.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D: A valuable compound for methodological research in organic chemistry and medicinal chemistry programs.
• Material Science: Potential intermediate for the synthesis of functional polymers and advanced materials.

Basic Information

Product Name	4-Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide
CAS No.	55261-00-2
Molecular Formula	C₄H₉NO₃S
Molecular Weight	151.18 g/mol
Synonyms	3-Hydroxy-4-aminotetrahydrothiophene 1,1-dioxide; 4-Amino-3-hydroxy-tetrahydrothiophene-1,1-dioxide; 3-Hydroxy-4-aminosulfolane; 4-Amino-3-hydroxysulfolane; Tetrahydro-3-hydroxy-4-amino-2-thiophene 1,1-dioxide; 4-Amino-3-hydroxy-2,3-dihydrothiophene 1,1-dioxide; 3-Hydroxy-4-aminothiolane 1,1-dioxide; Amino-hydroxy sulfolane
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Hydroxytetrahydrothiophene, 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.