Description

Phosphoric Acid (2,2-Diethoxyethyl)Bis(Trimethylsilyl) Ester is a specialized organosilicon-protected phosphate derivative, serving as a key reagent and synthetic intermediate in advanced organic synthesis. This compound matters for its role in introducing phosphate groups under mild, controlled conditions while offering enhanced stability and solubility in organic media. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules, modifying nucleosides, and developing novel functional materials.

Application

• Phosphorylation Reagent: Used for the selective phosphorylation of alcohols, amines, and other nucleophiles in the synthesis of nucleotides, phospholipids, and prodrugs.
• Nucleoside & Nucleotide Chemistry: A critical building block in the preparation of modified nucleosides, oligonucleotides, and their phosphoramidite derivatives for therapeutic and diagnostic applications.
• Agrochemical Synthesis: Employed as an intermediate in the production of certain organophosphate-based active ingredients and plant growth regulators.
• Material Science Precursor: Utilized in the surface modification of inorganic materials and the synthesis of flame-retardant or adhesion-promoting additives for polymers.
• Process Chemistry: Valued in scalable pharmaceutical manufacturing for its predictable reactivity and handling characteristics in multi-step synthetic sequences.
• Chemical Research: Serves as a versatile tool in academic and industrial laboratories for exploring new phosphorylation methodologies and creating novel chemical entities.

Basic Information

Product Name	Phosphoric Acid (2,2-Diethoxyethyl)Bis(Trimethylsilyl) Ester
CAS No.	55191-35-0
Molecular Formula	C14H35O6PSi2
Molecular Weight	386.58 g/mol
Synonyms	Bis(trimethylsilyl) (2,2-diethoxyethyl) phosphate; (2,2-Diethoxyethyl) Phosphoric Acid Bis(trimethylsilyl) Ester; Diethoxyethylbis(trimethylsilyl) Phosphate; Phosphoric Acid, (2,2-Diethoxyethyl)-, Bis(trimethylsilyl) Ester; TMS-Protected Diethoxyethyl Phosphate; Silyl Phosphorylating Agent; CAS 55191-35-0
EINECS	Contact for details

Quality Control

Our Phosphoric Acid (2,2-Diethoxyethyl)Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports research and development requiring reliable, high-purity synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.