Description

Pyrimidine, 2,4-Bis(Trimethylsilyl)- (9Ci) is a specialized organosilicon derivative of the pyrimidine heterocycle, serving as a valuable silyl-protected intermediate and building block in advanced synthetic chemistry. Its primary value lies in its ability to act as a masked nucleophile or a precursor for functionalized pyrimidines under mild conditions, enabling complex molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science sectors who require high-purity, reactive intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and other bioactive pyrimidine-based compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate the pyrimidine moiety.
• Organometallic & Catalysis Research: Serves as a ligand precursor or a substrate in cross-coupling reactions and other metal-catalyzed transformations.
• Materials Science: A precursor for creating functionalized organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) with tailored properties.
• Process Chemistry & Scale-up: Employed in route development and optimization for the commercial production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Pyrimidine, 2,4-Bis(Trimethylsilyl)- (9Ci)
CAS No.	55170-72-4
Molecular Formula	C10H22N2Si2
Molecular Weight	226.47 g/mol
Synonyms	2,4-Bis(trimethylsilyl)pyrimidine; 2,4-Bis(trimethylsilyl)pyrimidine (9CI); 2,4-Di(trimethylsilyl)pyrimidine; Pyrimidine, 2,4-bis(trimethylsilyl)-; 1,3-Bis(trimethylsilyl)pyrimidine-2,4(1H,3H)-dione (tautomer); NSC 406911; 2,4-Bis(trimethylsilyl)-1,3-diazine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2,4-Bis(Trimethylsilyl)- (9Ci) is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is assured through rigorous analytical testing, including NMR, HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.