Description

3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester is a versatile organosilicon reagent featuring a protected carboxylic acid functionality. This compound is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where protection of the carboxylic acid group is required during multi-step reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Employed as a protecting agent for carboxylic acids in solid-phase and solution-phase peptide synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of specialty silicones and functional polymers.
• Material Science: Utilized in surface modification and the creation of silane coupling agents to improve adhesion between organic and inorganic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for methodology development and the synthesis of complex natural products.

Basic Information

Product Name	3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester
CAS No.	55162-32-8
Molecular Formula	C9H22O3Si2
Molecular Weight	234.44 g/mol
Synonyms	3-(Trimethylsiloxy)propionic Acid Trimethylsilyl Ester; Trimethylsilyl 3-(Trimethylsiloxy)propanoate; Propanoic Acid, 3-(Trimethylsiloxy)-, Trimethylsilyl Ester; 3-(Trimethylsilyloxy)propanoic Acid Trimethylsilyl Ester; TMS-Protected 3-Hydroxypropionic Acid; Bis(trimethylsilyl) 3-Hydroxypropionate; 55162-32-8
EINECS	Contact for details

Quality Control

Our 3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.