Description

3-Methyl-2-[(Trimethylsilyl)Oxy]-2-Butenoic Acid Trimethylsilyl Ester is a specialized silyl-protected derivative of a β-ketoester, serving as a versatile and reactive synthetic intermediate. Its core value lies in providing a protected, moisture-sensitive functional group that enables precise transformations in complex organic syntheses under controlled conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring the introduction of protected carboxylic acid or ketone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive silyl ester group facilitates specific coupling reactions.
• Organic Synthesis Reagent: Acts as a protected synthon in multi-step laboratory-scale and pilot-scale organic reactions, including aldol condensations and nucleophilic additions.
• Material Science Research: Employed in the development of specialty polymers and fine chemicals that require precise molecular architecture.
• Process Chemistry: Utilized in route scouting and optimization for the commercial-scale manufacturing of high-value chemical products.

Basic Information

Product Name	3-Methyl-2-[(Trimethylsilyl)Oxy]-2-Butenoic Acid Trimethylsilyl Ester
CAS No.	55044-79-6
Molecular Formula	C11H24O3Si2
Molecular Weight	260.48 g/mol
Synonyms	2-Butenoic acid, 3-methyl-2-[(trimethylsilyl)oxy]-, trimethylsilyl ester; 3-Methyl-2-(trimethylsiloxy)-2-butenoic acid trimethylsilyl ester; Trimethylsilyl 3-methyl-2-(trimethylsiloxy)but-2-enoate; TMS ester of 3-methyl-2-(trimethylsiloxy)-2-butenoic acid; Bis(trimethylsilyl) 3-methyl-2-siloxy-2-butenoate
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-[(Trimethylsilyl)Oxy]-2-Butenoic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with batch-specific data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.