Description

1-Aza-Bicyclo[2.2.2]Octane-4-Carboxylic Acid is a high-purity bicyclic organic compound featuring a carboxylic acid functional group on a quinuclidine scaffold. This versatile building block is essential for synthesizing complex molecules in pharmaceutical research and fine chemical manufacturing. It is particularly valuable for medicinal chemists and R&D professionals developing novel active pharmaceutical ingredients (APIs), catalysts, and specialty ligands.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Catalyst & Ligand Synthesis: Used to construct sophisticated nitrogen-containing ligands for asymmetric catalysis and metal complexation.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical spaces and structure-activity relationships (SAR).
• Agrochemical Development: Employed in the synthesis of novel, high-performance crop protection agents and plant growth regulators.
• Material Science: A precursor for creating functionalized polymers and advanced organic materials with specific chemical properties.

Basic Information

Product Name	1-Aza-Bicyclo[2.2.2]Octane-4-Carboxylic Acid
CAS No.	55022-88-3
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	Quinuclidine-4-carboxylic Acid; 4-Quinuclidinecarboxylic Acid; 1-Azabicyclo[2.2.2]octane-4-carboxylic Acid; 4-Carboxyquinuclidine; 1-Azanorbornane-4-carboxylic Acid; 4-Quinuclidincarboxylic Acid; NSC 163022
EINECS	Contact for details

Quality Control

Our 1-Aza-Bicyclo[2.2.2]Octane-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.